Phase I study of imatinib, cisplatin and 5-fluoruracil or capecitabine in advanced esophageal and gastric adenocarcinoma

<p>Abstract</p> <p>Background</p> <p>Despite all benefit provided by established therapies prognosis of gastric cancer remains poor. Targeted inhibition of platelet derived growth factor receptor (PDGFR) by imatinib may influence tumor growth and amplify chemotherapeuti...

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Bibliographic Details
Main Authors: Mayr Martina, Becker Karen, Schulte Nadine, Belle Sebastian, Hofheinz Ralf, Krause Annekatrin, Schmid Roland M, Röcken Christoph, Ebert Matthias P
Format: Artigo
Language:Inglês
Published: BMC 2012-12-01
Series:BMC Cancer
Subjects:
Imatinib
PDGF
Gastric cancer
Chemotherapy
Online Access:http://www.biomedcentral.com/1471-2407/12/587
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