Phase I study of imatinib, cisplatin and 5-fluoruracil or capecitabine in advanced esophageal and gastric adenocarcinoma

<p>Abstract</p> <p>Background</p> <p>Despite all benefit provided by established therapies prognosis of gastric cancer remains poor. Targeted inhibition of platelet derived growth factor receptor (PDGFR) by imatinib may influence tumor growth and amplify chemotherapeuti...

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Bibliografiska uppgifter
Huvudupphovsmän: Mayr Martina, Becker Karen, Schulte Nadine, Belle Sebastian, Hofheinz Ralf, Krause Annekatrin, Schmid Roland M, Röcken Christoph, Ebert Matthias P
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMC 2012-12-01
Serie:BMC Cancer
Ämnen:
Imatinib
PDGF
Gastric cancer
Chemotherapy
Länkar:http://www.biomedcentral.com/1471-2407/12/587
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