A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction

Objective: Regulation of fatty acid (FA) metabolism is central to adipocyte dysfunction during diet-induced obesity (DIO). Long-chain acyl-CoA synthetase-4 (ACSL4) has been hypothesized to modulate the metabolic fates of polyunsaturated FA (PUFA), including arachidonic acid (AA), but the in vivo act...

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Main Authors: Elizabeth A. Killion, Andrew R. Reeves, Mahmoud A. El Azzouny, Qing-Wu Yan, Defne Surujon, John D. Griffin, Thomas A. Bowman, Chunyan Wang, Nirupa R. Matthan, Eric L. Klett, Dong Kong, John W. Newman, Xianlin Han, Mi-Jeong Lee, Rosalind A. Coleman, Andrew S. Greenberg
Format: Artigo
Language:Inglês
Published: Elsevier 2018-03-01
Series:Molecular Metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2212877817309626
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