A role for long-chain acyl-CoA synthetase-4 (ACSL4) in diet-induced phospholipid remodeling and obesity-associated adipocyte dysfunction

OBJECTIVE: Regulation of fatty acid (FA) metabolism is central to adipocyte dysfunction during diet-induced obesity (DIO). Long-chain acyl-CoA synthetase-4 (ACSL4) has been hypothesized to modulate the metabolic fates of polyunsaturated FA (PUFA), including arachidonic acid (AA), but the in vivo act...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Killion, Elizabeth A., Reeves, Andrew R., El Azzouny, Mahmoud A., Yan, Qing-Wu, Surujon, Defne, Griffin, John D., Bowman, Thomas A., Wang, Chunyan, Matthan, Nirupa R., Klett, Eric L., Kong, Dong, Newman, John W., Han, Xianlin, Lee, Mi-Jeong, Coleman, Rosalind A., Greenberg, Andrew S.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5870107/
https://ncbi.nlm.nih.gov/pubmed/29398618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.01.012
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