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Foxp3 interacts with c-Rel to mediate NF-κB repression.
Expression of the lineage-specific DNA-binding factor Foxp3 controls the development and function of naturally occurring regulatory T cells. Foxp3 has been shown to interact with a multitude of transcriptional regulators including NFAT, NF-κB (p65), Runx1 and RORγt, as well as the histone modificati...
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Autores principales: | , , |
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Formato: | Artigo |
Lenguaje: | Inglês |
Publicado: |
Public Library of Science (PLoS)
2011-04-01
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Colección: | PLoS ONE |
Acceso en línea: | http://europepmc.org/articles/PMC3072406?pdf=render |
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