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Foxp3 interacts with c-Rel to mediate NF-κB repression.

Expression of the lineage-specific DNA-binding factor Foxp3 controls the development and function of naturally occurring regulatory T cells. Foxp3 has been shown to interact with a multitude of transcriptional regulators including NFAT, NF-κB (p65), Runx1 and RORγt, as well as the histone modificati...

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Detalles Bibliográficos
Autores principales: Louiza Loizou, Kristian G Andersen, Alexander G Betz
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2011-04-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC3072406?pdf=render
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