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Metformin Ameliorates Inflammation and Airway Remodeling of Experimental Allergic Asthma in Mice by Restoring AMPKα Activity

Metformin has been involved in modulating inflammatory state and inhibiting cell proliferation and angiogenesis. This study aimed to determine whether metformin alleviates airway inflammation and remodeling of experimental allergic asthma and elucidate the underlying mechanism. We sensitized and cha...

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Main Authors: Wenxian Ma, Qiaoyan Jin, Haiqin Guo, Xinpeng Han, Lingbin Xu, Shemin Lu, Changgui Wu
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2022-01-01
叢編:Frontiers in Pharmacology
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在線閱讀:https://www.frontiersin.org/articles/10.3389/fphar.2022.780148/full
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