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Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia
Alterations in epithelial cell polarity and in the subcellular distributions of epithelial ion transport proteins are key molecular consequences of acute kidney injury and intracellular energy depletion. AMP-activated protein kinase (AMPK), a cellular energy sensor, is rapidly activated in response...
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| Hlavní autoři: | , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2011
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233870/ https://ncbi.nlm.nih.gov/pubmed/21849490 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00420.2010 |
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