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ATP- and Adenosine-Mediated Signaling in the Central Nervous System: Adenosine Stimulates Glutamate Release From Astrocytes via A2a Adenosine Receptors
Adenosine enhanced intracellular Ca2+ concentrations in astrocytes via A2a adenosine receptors involving protein kinase A (PKA) activation. The Ca2+ rise is inhibited by brefeldin A, an inhibitor of vesicular transport; but not by neomycin and U73122, phospholipase C inhibitors; xestospongin, an IP3...
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Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Elsevier
2004-01-01
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Serija: | Journal of Pharmacological Sciences |
Online dostop: | http://www.sciencedirect.com/science/article/pii/S1347861319325113 |
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