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Neuronal adenosine release, and not astrocytic ATP release, mediates feedback inhibition of excitatory activity
Adenosine is a potent anticonvulsant acting on excitatory synapses through A1 receptors. Cellular release of ATP, and its subsequent extracellular enzymatic degradation to adenosine, could provide a powerful mechanism for astrocytes to control the activity of neural networks during high-intensity ac...
Gorde:
| Egile Nagusiak: | , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2012
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3341061/ https://ncbi.nlm.nih.gov/pubmed/22421436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120997109 |
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