The Emerging Role of Zinc in the Pathogenesis of Multiple Sclerosis

Our lab has previously demonstrated that multiple sclerosis-induced spinal cord white matter damage and motor deficits are mediated by the pathological disruption of zinc homeostasis. Abnormal vesicular zinc release and intracellular zinc accumulation may mediate several steps in the pathophysiologi...

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Bibliographic Details
Main Authors: Bo Young Choi, Jong Won Jung, Sang Won Suh
Format: Artigo
Language:Inglês
Published: MDPI AG 2017-09-01
Series:International Journal of Molecular Sciences
Subjects:
multiple sclerosis
zinc
EAE
MMP-9 activation
BBB disruption
microglia activation
Online Access:https://www.mdpi.com/1422-0067/18/10/2070
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