Metformin modifies glutamine metabolism in an in vitro and in vivo model of hepatic encephalopathy

ABSTRACT Aim: to analyze the effect of metformin on ammonia production derived from glutamine metabolism in vitro and in vivo. Methods: twenty male Wistar rats were studied for 28 days after a porto-caval anastomosis (n = 16) or a sham operation (n = 4). Porto-caval shunted animals were randomized...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Antonio Gil-Gómez, Ana-Isabel Gómez-Sotelo, Isidora Ranchal, Ángela Rojas, Marta García-Valdecasas, Rocío Muñoz-Hernández, Rocío Gallego-Durán, Javier Ampuero, Manuel Romero-Gómez
Format: Artigo
Jezik:Inglês
Izdano: Aran Ediciones
Serija:Revista Espanola de Enfermedades Digestivas
Teme:
Hepatic encephalopathy
Metformin
Ammonia
Glutaminase
Glutamine
Cirrhosis
ASCT2
mTOR
Porto-caval anastomosis
Online dostop:http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S1130-01082018000700004&lng=en&tlng=en
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki