Roles of Anthrax Toxin Receptor 2 in Anthrax Toxin Membrane Insertion and Pore Formation

Interaction between bacterial toxins and cellular surface receptors is an important component of the host-pathogen interaction. Anthrax toxin protective antigen (PA) binds to the cell surface receptor, enters the cell through receptor-mediated endocytosis, and forms a pore on the endosomal membrane...

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Detalles Bibliográficos
Main Authors: Jianjun Sun, Pedro Jacquez
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2016-01-01
Series:Toxins
Assuntos:
anthrax
ANTXR2
pore formation
membrane translocation
pathogenesis
Acceso en liña:http://www.mdpi.com/2072-6651/8/2/34
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