Behavioral testing of minipigs transgenic for the Huntington gene-A three-year observational study.

Large animal models of Huntington's disease (HD) may increase the reliability of translating preclinical findings to humans. Long live expectancy offers opportunities particularly for disease modifying approaches, but also challenges. The transgenic (tg) HD minipig model assessed in this study...

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Главные авторы: Verena Schuldenzucker, Robin Schubert, Lisa M Muratori, Frauke Freisfeld, Lorena Rieke, Tamara Matheis, Sarah Schramke, Jan Motlik, Nicole Kemper, Ute Radespiel, Ralf Reilmann
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2017-01-01
Серии:PLoS ONE
Online-ссылка:http://europepmc.org/articles/PMC5633197?pdf=render
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