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Highly mutable tandem DNA repeats generate a cell wall protein variant more frequent in disease-causing Candida albicans isolates than in commensal isolates.

During adaptation to host environments, many microorganisms alter their cell surface. One mechanism for doing so is variation in the number of amino acid repeats in cell surface proteins encoded by hypermutable DNA tandem repeats. In the yeast Candida albicans, an opportunistic human pathogen, the g...

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Autores principales: Zhuo Zhou, Zoe Jordens, Shuguang Zhang, Ningxin Zhang, Jan Schmid
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2017-01-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC5491155?pdf=render
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