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Highly mutable tandem DNA repeats generate a cell wall protein variant more frequent in disease-causing Candida albicans isolates than in commensal isolates.

During adaptation to host environments, many microorganisms alter their cell surface. One mechanism for doing so is variation in the number of amino acid repeats in cell surface proteins encoded by hypermutable DNA tandem repeats. In the yeast Candida albicans, an opportunistic human pathogen, the g...

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Bibliografiske detaljer
Main Authors: Zhuo Zhou, Zoe Jordens, Shuguang Zhang, Ningxin Zhang, Jan Schmid
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science (PLoS) 2017-01-01
Serier:PLoS ONE
Online adgang:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0180246&type=printable
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