Načítá se...
A genetic assay for transcription errors reveals multilayer control of RNA polymerase II fidelity.
We developed a highly sensitive assay to detect transcription errors in vivo. The assay is based on suppression of a missense mutation in the active site tyrosine in the Cre recombinase. Because Cre acts as tetramer, background from translation errors are negligible. Functional Cre resulting from ra...
Uloženo v:
| Hlavní autoři: | , , , , , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science (PLoS)
2014-09-01
|
| Edice: | PLoS Genetics |
| On-line přístup: | http://europepmc.org/articles/PMC4168980?pdf=render |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|