Agonist Binding and G Protein Coupling in Histamine H<sub>2</sub> Receptor: A Molecular Dynamics Study

The histamine H<inline-formula><math display="inline"><semantics><msub><mrow></mrow><mn>2</mn></msub></semantics></math></inline-formula> receptor (H<sub>2</sub>R) plays an important role in the regulation...

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Main Authors: Marcus Conrad, Christian A. Söldner, Yinglong Miao, Heinrich Sticht
格式: Artigo
語言:Inglês
出版: MDPI AG 2020-09-01
叢編:International Journal of Molecular Sciences
主題:
receptor–ligand interactions
G protein-coupled receptors (GPCRs)
G<sub>s</sub> protein
ternary complex
molecular dynamics simulations
metadynamics
在線閱讀:https://www.mdpi.com/1422-0067/21/18/6693
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