3-O-Acyl-epicatechins Increase Glucose Uptake Activity and GLUT4 Translocation through Activation of PI3K Signaling in Skeletal Muscle Cells

Tea catechins promote glucose uptake in skeletal muscle cells. In this study, we investigated whether the addition of an acyl group to the C-3 position of catechins to generate 3-O-acyl-catechins promoted glucose uptake in L6 myotubes. 3-O-Myristoyl-(−)-epicatechin (EC-C14) and 3-O-palmitoyl-(−)-ep...

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Main Authors: Manabu Ueda-Wakagi, Rie Mukai, Naoya Fuse, Yoshiyuki Mizushina, Hitoshi Ashida
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2015-07-01
Colecção:International Journal of Molecular Sciences
Assuntos:
acyl catechin
glucose transporter 4
skeletal muscle
insulin signaling pathway
Acesso em linha:http://www.mdpi.com/1422-0067/16/7/16288
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