Genomic and Phenotypic Variation in Morphogenetic Networks of Two Candida albicans Isolates Subtends Their Different Pathogenic Potential

The transition from commensalism to pathogenicity of Candida albicans reflects both the host inability to mount specific immune responses and the microorganism’s dimorphic switch efficiency. In this study, we used whole genome sequencing and microarray analysis to investigate the genomic determinant...

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Main Authors: Duccio Cavalieri, Monica Di Paola, Lisa Rizzetto, Noemi Tocci, Carlotta De Filippo, Paolo Lionetti, Andrea Ardizzoni, Bruna Colombari, Simona Paulone, Ivo G. Gut, Luisa Berná, Marta Gut, Julie Blanc, Misha Kapushesky, Eva Pericolini, Elisabetta Blasi, Samuele Peppoloni
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-01-01
Serier:Frontiers in Immunology
Fag:
Candida albicans
host adaptation
biofilm
pathogenic traits
genomic
fungal isolates
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01997/full
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