The Beneficial Effects of Melatonin Administration Following Hypoxia-Ischemia in Preterm Fetal Sheep

Melatonin (MLT) is an endogenous hormone that controls circadian cycle. MLT has additional important properties that make it appealing as a neuroprotective agent—it is a potent anti-oxidant, with anti-apoptotic and anti-inflammatory properties. MLT is safe for administration during pregnancy or to t...

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Bibliographic Details
Main Authors: Tamara Yawno, Mawin Mahen, Jingang Li, Michael C. Fahey, Graham Jenkin, Suzanne L. Miller
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Cellular Neuroscience
Subjects:
melatonin
white matter injury
oligodendrocytes
preterm
fetal sheep
umbilical cord occlusion
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00296/full
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