Maternal melatonin administration mitigates coronary stiffness and endothelial dysfunction, and improves heart resilience to insult in growth restricted lambs

Intrauterine growth restriction (IUGR) is associated with impaired cardiac function in childhood and is linked to short- and long-term morbidities. Placental dysfunction underlies most IUGR, and causes fetal oxidative stress which may impact on cardiac development. Accordingly, we investigated wheth...

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Detalhes bibliográficos
Main Authors: Tare, Marianne, Parkington, Helena C, Wallace, Euan M, Sutherland, Amy E, Lim, Rebecca, Yawno, Tamara, Coleman, Harold A, Jenkin, Graham, Miller, Suzanne L
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2014
Assuntos:
Integrative
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4080947/
https://ncbi.nlm.nih.gov/pubmed/24710061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2014.270934
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