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Methyl donor supplementation blocks the adverse effects of maternal high fat diet on offspring physiology.

Maternal consumption of a high fat diet during pregnancy increases the offspring risk for obesity. Using a mouse model, we have previously shown that maternal consumption of a high fat (60%) diet leads to global and gene specific decreases in DNA methylation in the brain of the offspring. The presen...

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Bibliografische gegevens
Hoofdauteurs: Jesselea Carlin, Robert George, Teresa M Reyes
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science (PLoS) 2013-01-01
Reeks:PLoS ONE
Online toegang:http://europepmc.org/articles/PMC3642194?pdf=render
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