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P4.27 DIABETES-EVOKED PATHOGENIC CHANGES ASSOCIATED WITH ALTERED COPPER UPTAKE/TRANSPORT PATHWAYS IN THE AORTA OF STZ-DIABETIC RATS: EFFECTS OF TREATMENT BY CU(II)-SELECTIVE CHELATION
Objectives: Cardiovascular disease is the commonest complication of diabetes. Previous studies from our group have identified diabetes-evoked changes in copper homeostasis that cause accumulation of chelatable-Cu(II) in the heart (1). We also showed that treatment by Cu(II)-selective chelation with...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BMC
2013-11-01
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| Серии: | Artery Research |
| Online-ссылка: | https://www.atlantis-press.com/article/125939038/view |
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