The role of free radical oxidation in the kidneys in the nephroprotective action of eplerenone, a mineralocorticoid receptor antagonist, in experimental diabetes mellitus

Aim. To study the effect of eplerenone on the activity of free radical oxidation and renal function in rats with experimental diabetes mellitus induced by streptozotocin.Materials and methods. Experiments were carried out on 36 male Wistar rats. Diabetes mellitus (DM) was simulated by a single intra...

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Huvudupphovsmän: A. Yu. Zharikov, S. O. Filinova, O. N. Mazko, O. G. Makarova, I. P. Bobrov, V. M. Bryukhanov
Materialtyp: Artigo
Språk:Inglês
Publicerad: Siberian State Medical University (Tomsk) 2021-07-01
Serie:Bûlleten' Sibirskoj Mediciny
Ämnen:
eplerenone
free radical oxidation
diabetes mellitus
diabetic nephropathy
Länkar:https://bulletin.tomsk.ru/jour/article/view/4374
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