Mineralocorticoid Receptor Antagonists Eplerenone and Spironolactone Modify Adrenal Cortex Morphology and Physiology

Mineralocorticoid receptor antagonists (MRAs) are a class of anti-hypertensive drugs that act by blocking aldosterone action. The aim of this study was to evaluate whether the MRAs spironolactone and eplerenone influence adrenal cortical physiology and morphology. Spontaneous hypertensive rats (SHR,...

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Vydáno v:Biomedicines
Hlavní autoři: Pereira, Sofia S., Carvalho, Liliana, Costa, Madalena M., Melo, Armindo, Ferreira, Isabel M. P. L. V. O., Gomez-Sanchez, Celso E., Monteiro, Mariana P., Vinson, Gavin, Pignatelli, Duarte
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2021
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8074383/
https://ncbi.nlm.nih.gov/pubmed/33924172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines9040441
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