PTH (1-34) enhances the therapeutic effect of bone marrow mesenchymal stem cell-derived exosomes by inhibiting proinflammatory cytokines expression on OA chondrocyte repair in vitro

Abstract Background The effects of bone marrow mesenchymal stem cells (BMSCs) during the treatment of cartilage damage have been proven to be attributed to paracrine mechanisms, particularly the effect of exosomes. Exosomes from different batches are inhomogeneous, and different treatment effects ar...

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Main Authors: Li-tao Shao, Liang Luo, Jie-hong Qiu, David Y. B. Deng
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-04-01
Colecção:Arthritis Research & Therapy
Assuntos:
Osteoarthritis
Parathyroid hormone
Exosome
Chondrocyte
Acesso em linha:https://doi.org/10.1186/s13075-022-02778-x
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