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Catabolic and proinflammatory effects of leptin in chondrocytes are regulated by suppressor of cytokine signaling-3
BACKGROUND: Previous studies provide evidence that adipokine leptin increases production of catabolic and proinflammatory factors in chondrocytes and serves as a link between obesity and osteoarthritis (OA). However, the magnitude of the response to leptin treatment varies greatly between chondrocyt...
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Publicado no: | Arthritis Res Ther |
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Main Authors: | , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048607/ https://ncbi.nlm.nih.gov/pubmed/27716333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1112-0 |
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