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Catabolic and proinflammatory effects of leptin in chondrocytes are regulated by suppressor of cytokine signaling-3

BACKGROUND: Previous studies provide evidence that adipokine leptin increases production of catabolic and proinflammatory factors in chondrocytes and serves as a link between obesity and osteoarthritis (OA). However, the magnitude of the response to leptin treatment varies greatly between chondrocyt...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Koskinen-Kolasa, Anna, Vuolteenaho, Katriina, Korhonen, Riku, Moilanen, Teemu, Moilanen, Eeva
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5048607/
https://ncbi.nlm.nih.gov/pubmed/27716333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-016-1112-0
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