Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.

Protein kinase CK2 is frequently up-regulated in human cancers, although the mechanism of CK2 activation in cancer remains unknown. In this study, we investigated the role of the CK2alpha intronless gene (CSNK2A1P, a presumed CK2alpha pseudogene) in the pathogenesis of human cancers. We found eviden...

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Autores principales: Ming-Szu Hung, Yu-Ching Lin, Jian-Hua Mao, Il-Jin Kim, Zhidong Xu, Cheng-Ta Yang, David M Jablons, Liang You
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science (PLoS) 2010-07-01
Colección:PLoS ONE
Acceso en línea:http://europepmc.org/articles/PMC2896393?pdf=render
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