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Molecular pathogenesis of long QT syndrome type 1

Long QT syndrome type 1 (LQT1) is a subtype of a congenital cardiac syndrome caused by mutation in the KCNQ1 gene, which encodes the α-subunit of the slow component of delayed rectifier K+ current (IKs) channel. Arrhythmias in LQT1 are characterized by prolongation of the QT interval on ECG, as well...

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Hlavní autoři: Jie Wu, PhD, Wei-Guang Ding, MD, PhD, Minoru Horie, MD, PhD
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley 2016-10-01
Edice:Journal of Arrhythmia
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On-line přístup:http://www.sciencedirect.com/science/article/pii/S1880427616000041
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