Insulin-Dependent H2O2 Production Is Higher in Muscle Fibers of Mice Fed with a High-Fat Diet

Insulin resistance is defined as a reduced ability of insulin to stimulate glucose utilization. C57BL/6 mice fed with a high-fat diet (HFD) are a model of insulin resistance. In skeletal muscle, hydrogen peroxide (H2O2) produced by NADPH oxidase 2 (NOX2) is involved in signaling pathways triggered b...

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Detalhes bibliográficos
Main Authors: Ariel Contreras-Ferrat, Paola Llanos, Rodrigo Valenzuela, Gladys Tapia, José L. Bucarey, César Osorio-Fuentealba, Nevenka Juretic, José E. Galgani, Alexis Díaz-Vegas, Cristian Campos, Alejandra Espinosa, Enrique Jaimovich
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2013-07-01
Colecção:International Journal of Molecular Sciences
Assuntos:
obesity
NOX2
insulin resistance
apocynin
Acesso em linha:http://www.mdpi.com/1422-0067/14/8/15740
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