A strategy for eliciting antibodies against cryptic, conserved, conformationally dependent epitopes of HIV envelope glycoprotein.

Novel strategies are needed for the elicitation of broadly neutralizing antibodies to the HIV envelope glycoprotein, gp120. Experimental evidence suggests that combinations of antibodies that are broadly neutralizing in vitro may protect against challenge with HIV in nonhuman primates, and a small n...

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Main Authors: Hanna C Kelker, Vincenza R Itri, Fred T Valentine
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science (PLoS) 2010-01-01
סדרה:PLoS ONE
גישה מקוונת:http://europepmc.org/articles/PMC2797330?pdf=render
תגים: הוספת תג
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