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A strategy for eliciting antibodies against cryptic, conserved, conformationally dependent epitopes of HIV envelope glycoprotein.

Novel strategies are needed for the elicitation of broadly neutralizing antibodies to the HIV envelope glycoprotein, gp120. Experimental evidence suggests that combinations of antibodies that are broadly neutralizing in vitro may protect against challenge with HIV in nonhuman primates, and a small n...

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Hlavní autoři: Hanna C Kelker, Vincenza R Itri, Fred T Valentine
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2010-01-01
Edice:PLoS ONE
On-line přístup:http://europepmc.org/articles/PMC2797330?pdf=render
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