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Androgens upregulate Cdc25C protein by inhibiting its proteasomal and lysosomal degradation pathways.
Cdc25C is a cell cycle protein of the dual specificity phosphatase family essential for activating the cdk1/Cyclin B1 complex in cells entering into mitosis. Since altered cell cycle is a hallmark of human cancers, we investigated androgen regulation of Cdc25C protein in human prostate cancer (PCa)...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Public Library of Science (PLoS)
2013-01-01
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| Sarja: | PLoS ONE |
| Linkit: | http://europepmc.org/articles/PMC3630140?pdf=render |
| Tagit: |
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