Učitavanje...
ATG5 is essential for ATG8-dependent autophagy and mitochondrial homeostasis in Leishmania major.
Macroautophagy has been shown to be important for the cellular remodelling required for Leishmania differentiation. We now demonstrate that L. major contains a functional ATG12-ATG5 conjugation system, which is required for ATG8-dependent autophagosome formation. Nascent autophagosomes were found co...
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| Glavni autori: | , , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Public Library of Science (PLoS)
2012-01-01
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| Serija: | PLoS Pathogens |
| Online pristup: | http://europepmc.org/articles/PMC3355087?pdf=render |
| Oznake: |
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