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Exploring Synergy in Combinations of Tumor-Derived Vaccines That Harbor 4-1BBL, OX40L, and GM-CSF

Recent studies have demonstrated that combination of modulatory immune strategies may potentiate tumor cell elimination. Most strategies rely on the use of monoclonal antibodies that can block cell surface receptors to overcome tumor-induced immunosuppression or acting as costimulatory ligands to bo...

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Main Authors: Andrea J. Manrique-Rincón, Camila M. Beraldo, Jessica M. Toscaro, Marcio C. Bajgelman
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2017-09-01
Colecção:Frontiers in Immunology
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Acesso em linha:http://journal.frontiersin.org/article/10.3389/fimmu.2017.01150/full
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