Targeting the Type 5 Metabotropic Glutamate Receptor: A Potential Therapeutic Strategy for Neurodegenerative Diseases?

The type 5 metabotropic glutamate receptor, mGlu5, has been proposed as a potential therapeutic target for the treatment of several neurodegenerative diseases. In preclinical neurodegenerative disease models, novel allosteric modulators have been shown to improve cognitive performance and reduce dis...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Rebecca F. Budgett, Geor Bakker, Eugenia Sergeev, Kirstie A. Bennett, Sophie J. Bradley
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2022-05-01
श्रृंखला:Frontiers in Pharmacology
विषय:
GPCR
Alzheimer’s disease
neurodegenerative disease
neuroinflammation
G protein coupled receptors
drug discovery
ऑनलाइन पहुंच:https://www.frontiersin.org/articles/10.3389/fphar.2022.893422/full
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