A Two-Phase Expansion Protocol Combining Interleukin (IL)-15 and IL-21 Improves Natural Killer Cell Proliferation and Cytotoxicity against Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is the most common soft tissue malignancy in children. Despite intensive research in recent decades the prognosis for patients with metastatic or relapsed diseases has hardly improved. New therapeutic concepts in anti-tumor therapy aim to modulate the patient’s immune system t...

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Autori principali: Juliane Wagner, Viktoria Pfannenstiel, Anja Waldmann, Judith W. J. Bergs, Boris Brill, Sabine Huenecke, Thomas Klingebiel, Franz Rödel, Christian J. Buchholz, Winfried S. Wels, Peter Bader, Evelyn Ullrich
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2017-06-01
Serie:Frontiers in Immunology
Soggetti:
natural killer cells
radiotherapy
rhabdomyosarcoma
RH30 cells
RD cells
interleukin-15
Accesso online:http://journal.frontiersin.org/article/10.3389/fimmu.2017.00676/full
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