Deficiency of fibroblast growth factor 21 (FGF21) promotes hepatocellular carcinoma (HCC) in mice on a long term obesogenic diet

Objective: Non-alcoholic fatty liver (NAFL) associated with obesity is a major cause of liver diseases which can progress to non-alcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma (HCC). Fibroblast growth factor 21 (FGF21) plays an important role in liver metabolism and is also a pot...

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Hlavní autoři: Garima Singhal, Gaurav Kumar, Suzanne Chan, ffolliott M. Fisher, Yong Ma, Hilde G. Vardeh, Imad A. Nasser, Jeffrey S. Flier, Eleftheria Maratos-Flier
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018-07-01
Edice:Molecular Metabolism
On-line přístup:http://www.sciencedirect.com/science/article/pii/S2212877818301091
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