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Alphalipoic Acid Prevents Oxidative Stress and Peripheral Neuropathy in Nab-Paclitaxel-Treated Rats through the Nrf2 Signalling Pathway

Peripheral neuropathy is the major dose-limiting side effect of paclitaxel (PTX), affecting both the quality of life and the survival of cancer patients. Nab-paclitaxel (nab-PTX) was developed to provide additional clinical benefits and overcome the safety drawbacks of solvent-based PTX. However, th...

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Detalhes bibliográficos
Main Authors: Hong Sun, Xi Guo, Ziteng Wang, Peipei Wang, Zhe Zhang, Jihong Dong, Rongyuan Zhuang, Yuhong Zhou, Guo Ma, Weimin Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Limited 2019-01-01
Colecção:Oxidative Medicine and Cellular Longevity
Acesso em linha:http://dx.doi.org/10.1155/2019/3142732
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