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IRF4 Activity Is Required in Established Plasma Cells to Regulate Gene Transcription and Mitochondrial Homeostasis

Summary: The transcription factor interferon regulatory factor 4 (IRF4) is critical for the development, maintenance, and function of plasma cells. The mechanism by which IRF4 exerts its action in mature plasma cells has been elusive due to the death of all such cells upon IRF4 loss. While we identi...

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書誌詳細
主要な著者: Michael Sze Yuan Low, Erica J. Brodie, Pasquale L. Fedele, Yang Liao, George Grigoriadis, Andreas Strasser, Axel Kallies, Simon N. Willis, Julie Tellier, Wei Shi, Sarah Gabriel, Kristy O’Donnell, Catherine Pitt, Stephen L. Nutt, David Tarlinton
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2019-11-01
シリーズ:Cell Reports
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S2211124719314305
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