Exosomal microRNAs shuttling between tumor cells and macrophages: cellular interactions and novel therapeutic strategies

Abstract Extracellular vesicles secreted by tumor microenvironment (TME) cells are vital players in tumor progression through transferring nucleic acids and proteins. Macrophages are the main immune cells in TME and tumor associated macrophages (TAM) express M2 phenotype, which induce tumor prolifer...

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Detalhes bibliográficos
Main Authors: Wen-Xiu Xu, Dan-Dan Wang, Zhi-Qiang Zhao, He-Da Zhang, Su-Jin Yang, Qian Zhang, Lei Li, Jian Zhang
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2022-05-01
Colecção:Cancer Cell International
Assuntos:
Extracellular vesicles
Tumor associated macrophages
Cancers
Tumorigenesis
Tumor microenvironment
Acesso em linha:https://doi.org/10.1186/s12935-022-02594-y
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