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STIM1 Deficiency In Intestinal Epithelium Attenuates Colonic Inflammation and Tumorigenesis by Reducing ER Stress of Goblet CellsSummary

Background & Aims: As an indispensable component of store-operated Ca2+ entry, stromal interaction molecule 1 (STIM1) is known to promote colorectal cancer and T-cell–mediated inflammatory diseases. However, whether the intestinal mucosal STIM1 is involved in inflammatory bowel diseases (IBD...

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Main Authors: Xiaojing Liang, Jiansheng Xie, Hao Liu, Rongjie Zhao, Wei Zhang, Haidong Wang, Hongming Pan, Yubin Zhou, Weidong Han
格式: Artigo
語言:Inglês
出版: Elsevier 2022-01-01
叢編:Cellular and Molecular Gastroenterology and Hepatology
主題:
IBD
在線閱讀:http://www.sciencedirect.com/science/article/pii/S2352345X22000595
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