The Traditional Japanese Herbal Medicine Hachimijiogan Elicits Neurite Outgrowth Effects in PC12 Cells and Improves Cognitive in AD Model Rats via Phosphorylation of CREB

Hachimijiogan (HJG) is a traditional herbal medicine that improves anxiety disorders in patients with dementia. In this study, we tested the hypothesis that HJG exerts neurotrophic factor-like effects to ameliorate memory impairment in Alzheimer disease (AD) model rats. First, we describe that HJG a...

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Библиографические подробности
Главные авторы: Kaori Kubota, Haruka Fukue, Hitomi Sato, Kana Hashimoto, Aya Fujikane, Hiroshi Moriyama, Takuya Watanabe, Shutaro Katsurabayashi, Mosaburo Kainuma, Katsunori Iwasaki
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2017-11-01
Серии:Frontiers in Pharmacology
Предметы:
Alzheimer’s disease
Hachimijiogan
neurotrophic factors
CREB
PC12 cells
Online-ссылка:http://journal.frontiersin.org/article/10.3389/fphar.2017.00850/full
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