Active Tuberculosis Is Characterized by Highly Differentiated Effector Memory Th1 Cells

Despite advances in diagnosing latent Mycobacterium tuberculosis infection (LTBI), we still lack a diagnostic test that differentiates LTBI from active tuberculosis (TB) or predicts the risk of progression to active disease. One reason for the absence of such a test may be the failure of current ass...

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Main Authors: Riccardo Arrigucci, Karim Lakehal, Pooja Vir, Deborah Handler, Amy L. Davidow, Rosa Herrera, Julia Dolores Estrada-Guzmán, Yuri Bushkin, Sanjay Tyagi, Alfred A. Lardizabal, Maria Laura Gennaro
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018-09-01
Colecção:Frontiers in Immunology
Assuntos:
FISH-Flow
T cell activation
cytokine
immunophenotyping
single-cell gene expression
memory T cells
Acesso em linha:https://www.frontiersin.org/article/10.3389/fimmu.2018.02127/full
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