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CDK4/6 inhibition in breast cancer: current practice and future directions

The cyclin D/cyclin-dependent kinases 4 and 6 (CDK4/6)–retinoblastoma protein (RB) pathway plays a key role in the proliferation of both normal breast epithelium and breast cancer cells. A strong rationale for inhibiting CDK4/6 in breast cancers has been present for many years. However, potent and s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sonia Pernas, Sara M. Tolaney, Eric P. Winer, Shom Goel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publishing 2018-07-01
Cyfres:Therapeutic Advances in Medical Oncology
Mynediad Ar-lein:https://doi.org/10.1177/1758835918786451
Tagiau: Ychwanegu Tag
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