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Multifaceted effects of synthetic TLR2 ligand and <it>Legionella pneumophilia </it>on Treg-mediated suppression of T cell activation

<p>Abstract</p> <p>Background</p> <p>Regulatory T cells (Treg) play a crucial role in maintaining immune homeostasis and self-tolerance. The immune suppressive effects of Tregs should however be limited in case effective immunity is required against pathogens or cancer...

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Hlavní autoři: Sutmuller Roger PM, Bolscher Judith M, Toonen Liza W, Nierkens Stefan, van Maren Wendy WC, Adema Gosse J
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2011-03-01
Edice:BMC Immunology
On-line přístup:http://www.biomedcentral.com/1471-2172/12/23
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