Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice

Abstract Background Sodium glucose co-transporter2 inhibitors reduce the incidence of cardiovascular events in patients with type 2 diabetes mellitus based on the results of recent cardiovascular outcome studies. Herein, we investigated the effects of long-term treatment with canagliflozin on bioche...

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Bibliographic Details
Main Authors: Νarjes Nasiri-Ansari, Georgios K. Dimitriadis, Georgios Agrogiannis, Despoina Perrea, Ioannis D. Kostakis, Gregory Kaltsas, Athanasios G. Papavassiliou, Harpal S. Randeva, Eva Kassi
Format: Artigo
Language:Inglês
Published: BMC 2018-07-01
Series:Cardiovascular Diabetology
Subjects:
Canagliflozin
SGLT2i
Atherosclerosis
Inflammation
APOE knockout mice
Online Access:http://link.springer.com/article/10.1186/s12933-018-0749-1
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