Pleiotropic association of LIPC variants with lipid and urinary 8-hydroxy deoxyguanosine levels in a Taiwanese population

Abstract Background Hepatic lipase (HL, encoded by LIPC) is a glycoprotein primarily synthesized and secreted by hepatocytes. Previous studies had demonstrated that HL is crucial for reverse cholesterol transport and affects the metabolism, composition, and level of several lipoproteins. In current...

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Bibliografische gegevens
Hoofdauteurs: Ming-Sheng Teng, Semon Wu, Lung-An Hsu, I-Shiang Tzeng, Hsin-Hua Chou, Cheng-Wen Su, Yu-Lin Ko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BMC 2019-05-01
Reeks:Lipids in Health and Disease
Onderwerpen:
Hepatic lipase
Single-nucleotide polymorphism
Mediation analysis
Suppression effect
Triglyceride level
High-density lipoprotein cholesterol level
Online toegang:http://link.springer.com/article/10.1186/s12944-019-1057-9
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