Pleiotropic association of LIPC variants with lipid and urinary 8-hydroxy deoxyguanosine levels in a Taiwanese population

Abstract Background Hepatic lipase (HL, encoded by LIPC) is a glycoprotein primarily synthesized and secreted by hepatocytes. Previous studies had demonstrated that HL is crucial for reverse cholesterol transport and affects the metabolism, composition, and level of several lipoproteins. In current...

Full beskrivning

Sparad:
Bibliografiska uppgifter
Huvudupphovsmän: Ming-Sheng Teng, Semon Wu, Lung-An Hsu, I-Shiang Tzeng, Hsin-Hua Chou, Cheng-Wen Su, Yu-Lin Ko
Materialtyp: Artigo
Språk:Inglês
Publicerad: BMC 2019-05-01
Serie:Lipids in Health and Disease
Ämnen:
Hepatic lipase
Single-nucleotide polymorphism
Mediation analysis
Suppression effect
Triglyceride level
High-density lipoprotein cholesterol level
Länkar:http://link.springer.com/article/10.1186/s12944-019-1057-9
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk