Pleiotropic association of LIPC variants with lipid and urinary 8-hydroxy deoxyguanosine levels in a Taiwanese population

Abstract Background Hepatic lipase (HL, encoded by LIPC) is a glycoprotein primarily synthesized and secreted by hepatocytes. Previous studies had demonstrated that HL is crucial for reverse cholesterol transport and affects the metabolism, composition, and level of several lipoproteins. In current...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Ming-Sheng Teng, Semon Wu, Lung-An Hsu, I-Shiang Tzeng, Hsin-Hua Chou, Cheng-Wen Su, Yu-Lin Ko
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: BMC 2019-05-01
Σειρά:Lipids in Health and Disease
Θέματα:
Hepatic lipase
Single-nucleotide polymorphism
Mediation analysis
Suppression effect
Triglyceride level
High-density lipoprotein cholesterol level
Διαθέσιμο Online:http://link.springer.com/article/10.1186/s12944-019-1057-9
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